Regulation of blood fat transport following a fatty test meal in lean men and men with the metabolic syndrome

This study is looking at how the body processes fats after eating a high-fat meal in men who have metabolic syndrome (a cluster of health problems including a large waist, high blood fats, and high blood sugar) compared to lean, healthy men. Some of the men with metabolic syndrome will also be taking a cholesterol-lowering drug (Crestor/rosuvastatin). This will help researchers understand how the body handles dietary fat in these different groups. You may be eligible if: - You are a man between 20 and 75 years old - You are a non-smoker - You have metabolic syndrome (with at least 3 of the defining features) OR you are a lean, healthy man with normal blood lipid levels - Your BMI is below 40 (metabolic syndrome group) or below 25 (lean group) You may NOT be eligible if: - You have diabetes mellitus - You have a genetic cholesterol disorder - You drink more than 30 grams of alcohol per day - You have significant liver, kidney, or thyroid problems - You have had a heart attack or cardiovascular event in the past 6 months - You are on a very low-calorie diet or have lactose intolerance Talk to your doctor about whether this trial might be right for you.