RecruitingACTRN12609000671268

Dysphagia in Inflammatory Muscle Diseases: Answering the Questions Who, Where, Why and What to Do?


Sponsor

Sir Charles Gairdner Hospital

Enrollment

70 participants

Start Date

Aug 1, 2009

Study Type

Observational

Conditions

Summary

This study aims to better investigate the underlying problem behind the swallowing difficulties (dysphagia) experienced by many people diagnosed with inflammatory muscle disorders (Inclusion Body Myositis, Dermatomyositis and Polymyositis)


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 90 Yearss

Inclusion Criteria3

  • diagnosed with inflammatory muscle diseases
  • able to provide informed consent
  • no surgical interventions to head/neck

Exclusion Criteria3

  • unable to provide consent
  • surgical intervention to head/neck
  • any other neurological condition

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Interventions

using videofluoroscopy and manometry to investigate the mechanisms behind swallowing problems reported by patients with inflammatory muscle diseases Videofluoroscopy is a procedure where patients ing

using videofluoroscopy and manometry to investigate the mechanisms behind swallowing problems reported by patients with inflammatory muscle diseases Videofluoroscopy is a procedure where patients ingest radioopaque barium sulphaate mixed with small amounts of food/fluids. The procedure is x-rayed using a fluoroscope and recorded to allow frame-by-frame analysis of the swallowing dynamic. The procedure exposes patients to small amounts of ionising radiation (calculated as 0.2 milliseiverts). The Videofluoroscopy will be performed simulataneously with a manometric examination of the swallow. Participants have a purpose built manometric catheter (outside diameter 2.0 mm) inserted via the nares and positioned in the upper oesophageal sphincter. Recordings of upper oesophageal sphincter, oesophageal and pharyngeal pressures will be recorded. TOTAL time for both procedures =30 minutes approx.


Locations(1)

Australia

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ACTRN12609000671268