Randomised, Placebo Controlled Trial of Ropivocain Wound Infusion in Laparoscopic Colonic Resection
Do patients who undergo laparoscopic colonic resections who receive ropivocain wound infusions, compared to normal saline infusions have better postoperative pain relief with reduced requirements for opioids.
Dr Steve Smith
50 participants
Jan 31, 2007
Interventional
Conditions
Summary
The aim of this study is to determine if the use of local anaesthetic infusion into the surgical incision is effective in reducing pain following laparoscopic (keyhole) colonic resections (removal of sections of large bowel). It difficult to predict the outcome of this paper as laparoscopic surgery uses only small incisions which will generate a smaller proportion of the total postoperative pain felt compared to the pain generated from the intraabdominal surgical site which has not been altered through this technique.
Eligibility
Inclusion Criteria1
- all patients booked for elective laparoscopic colonic resection over the age of 18 who are able to give informed consent
Exclusion Criteria3
- renal failure
- chronic pain syndromes or already on long term analgesia, regardless of indication
- urgent or emergency procedures
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Ropivocain (a form of local anaesthetic) infusion (10mL/hr) at the surgical incision site using fine bore catheter inserted at the time of wound closure. Infusion commences upon application of the wound dressings and continues until postoperative day 3. At this time the catheter is to be removed by nursing staff on the ward 72 hours after the infusion started. Laparoscopic procedures are best known as keyhole procedures and involve using long instruments to manipulate the organs within the abdomen through very small incisions. Colonic resection refers to the removal of a part of the large bowel for a variety of indications although the most common indications are sepsis due to local perforation and malignancy.
Locations(1)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12609000745246