CompletedPhase 2ACTRN12609000745246

Randomised, Placebo Controlled Trial of Ropivocain Wound Infusion in Laparoscopic Colonic Resection

Do patients who undergo laparoscopic colonic resections who receive ropivocain wound infusions, compared to normal saline infusions have better postoperative pain relief with reduced requirements for opioids.

Sponsor

Dr Steve Smith

Enrollment

50 participants

Start Date

Jan 31, 2007

Study Type

Interventional

Conditions

pain relief following laparoscopic colorectal surgery

Summary

The aim of this study is to determine if the use of local anaesthetic infusion into the surgical incision is effective in reducing pain following laparoscopic (keyhole) colonic resections (removal of sections of large bowel). It difficult to predict the outcome of this paper as laparoscopic surgery uses only small incisions which will generate a smaller proportion of the total postoperative pain felt compared to the pain generated from the intraabdominal surgical site which has not been altered through this technique.

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 100 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether continuously infusing a local anaesthetic (ropivacaine) into the surgical wound after keyhole bowel surgery reduces pain compared to a placebo. It is open to adults aged 18 and older having planned laparoscopic colon surgery.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Ropivocain (a form of local anaesthetic) infusion (10mL/hr) at the surgical incision site using fine bore catheter inserted at the time of wound closure. Infusion commences upon application of the wound dressings and continues until postoperative day 3. At this time the catheter is to be removed by nursing staff on the ward 72 hours after the infusion started. Laparoscopic procedures are best known as keyhole procedures and involve using long instruments to manipulate the organs within the abdomen through very small incisions. Colonic resection refers to the removal of a part of the large bowel for a variety of indications although the most common indications are sepsis due to local perforation and malignancy.

Locations(1)

Australia

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12609000745246