ActivePhase 2Phase 3ACTRN12609000748213

A targeted community program of vitamin D treatment to reduce hospital admissions for falls, fractures and other disorders

A randomised controlled placebo-controlled study to evaluate the effects of vitamin D treatment on reducing hospital admissions for falls, fractures and other disorders in elderly women


Sponsor

Professor RL Prince

Enrollment

660 participants

Start Date

Feb 1, 2009

Study Type

Interventional

Conditions

Summary

This is a nine-month randomised controlled study to evaluate the effects of vitamin D 150,000 IU per three months on risk of falling, serum vitamin D levels, mobility function and muscle strength in women aged 70 years and over at a community setting.


Eligibility

Sex: FemalesMin Age: 70 Yearss

Inclusion Criteria4

  • Females age over 70;
  • a) Registered with a General Practitioner (GP) attached to the practices selected for the study or
  • b) Registered with a General Practitioner and able to contact her General Practitioner in Perth;
  • Likely to be able to attend their General Practitioner practice or Sir Charles Gairdner Hospital for four study visits over nine months.

Exclusion Criteria3

  • Consuming a vitamin D supplement either in isolation or as part of a combination treatment of greater than 200 IU per day, eg. Actonel combi +D or Fosamax plus;
  • A mini mental state score of less than 24;
  • Individuals who in the investigators opinion would not be suitable for the study.

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Interventions

150,000 IU vitamin D (cholecalciferol) taken orally as 3 capsules at three clinic visits three months apart; lifestyle advice on physical activity and calcium intake given at baseline through an infor

150,000 IU vitamin D (cholecalciferol) taken orally as 3 capsules at three clinic visits three months apart; lifestyle advice on physical activity and calcium intake given at baseline through an information sheet administered by trained research assistants


Locations(1)

Australia

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