RecruitingACTRN12609000842268

Observational study assessing the laryngeal and pharyngeal spread of topical local anaesthetic administered orally during general anaesthesia in children


Sponsor

Royal Childerns Hospital, Melbourne

Enrollment

120 participants

Start Date

Feb 1, 2008

Study Type

Observational

Conditions

Summary

This study has been designed to determine the effectiveness of a routine anaesthetic practice at the Royal Children's Hospital (RCH) in Melbourne. At this institution, we pour local anaesthetic into the pharynx (throat) of children having general anaesthesia with a tracheal tube (breathing tube) in the hope that the larynx will become partially anaesthetised in order to reduce adverse events during anaesthesia such as coughing, laryngospasm (the vocal cords clamping together), oxygen levels dropping in the patient's blood, or slowing of heart rate.


Eligibility

Sex: Both males and femalesMin Age: 6 MonthssMax Age: 16 Yearss

Plain Language Summary

Simplified for easier understanding

This study is observing a routine practice at the Royal Children's Hospital in Melbourne, where a numbing medicine (local anaesthetic) is poured into a child's throat during general anaesthesia. Doctors do this hoping it will reduce unpleasant reactions when the breathing tube is removed, such as coughing or the airway clamping shut. Researchers want to measure how far the local anaesthetic spreads and whether it actually numbs the right areas. You may be eligible if: - Your child is between 6 months and 16 years old - Your child is generally healthy (no significant medical problems) - Your child is having planned (elective) surgery that requires a breathing tube You may NOT be eligible if: - Your child has significant medical problems (classified as ASA grade 3 or above by the anaesthesia team) Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Observational study to assess the spread of local anaesthetic solution throughout the pharynx and larynx. Children having a general anaesthetic requiring a tracheal tube will have local anaesthetic

Observational study to assess the spread of local anaesthetic solution throughout the pharynx and larynx. Children having a general anaesthetic requiring a tracheal tube will have local anaesthetic poured into the back of the mouth. The local anaesthetic will be stained with methylene blue dye, so that the investigator is able to determine which parts of the patient have come into contact with the local anaesthetic. The study is expected to be completed within two years.


Locations(1)

Australia

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ACTRN12609000842268