Pharmacokinetics of 0.25% levobupivacaine with adrenaline following caudal epidural administration in children
A non-randomised single group study on the pharmokinetics of 0.25% levobupivacaine with adrenaline administered caudally in children undergoing elective sub-umbilical surgical procedures for which caudal epidural analgesia is indicated
Royal Children's Hospital
60 participants
Dec 8, 2009
Interventional
Conditions
Summary
The aim of this study is to determine how adrenaline affects the absorption of levobupivacaine in children having caudal anaesthesia for sub-umbilical surgery. Our study hypothesis is that the absorption of levobupivacaine will be affected when administered in conjunction with adrenaline via the caudal route.
Eligibility
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Interventions
Participants will receive 0.25% levobupivacaine in a volume to be determined by the attending anaesthetist with adrenaline 5 mcg/mL via the caudal route, under general anaesthesia. This will be administered as a single shot caudal.
Locations(1)
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ACTRN12609000845235