Randomized clinical trial of the influence of intraperitoneal local anesthesia on pain after laparoscopic colectomy
Randomized clinical trial of the influence of intraperitoneal local anesthesia on pain after laparoscopic colectomy.
Chuna-Ang University
60 participants
Dec 1, 2009
Interventional
Conditions
Summary
The aim of this study is to examine the effect of intraperitoneal LA on the requirement for postoperative and pain intensity after long duration of pneumoperitoneum. We also hypothesize that the timing of administration of intraperitoneal local anesthetics(LA) will affect to postoperative pain.
Eligibility
Inclusion Criteria1
- Patients will be scheduled to undergo elective laparoscopic colectomy.
Exclusion Criteria2
- Patients weigh under 45 kg or over 100 kg,
- have severe underlying cardiovascular, renal, hepatic diseases, and have allergy to local anesthetics will be excluded.
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Interventions
There are three groups in total: Group I(infiltration), Group D(Double0, Group C( Control). Group I(Infiltration) : infiltration ropivacaine only at the beginning of the surgery Group D(Double) : infiltration ropivacaine twice during the surgery (time of start and end of surgery) Immediately after creation of pneumoperitoneum and place of the first two trocars 1 mg/kg of ropivacaine in 100 ml normal saline in Group I and Group D will be sprayed on the upper surface of right and left lobe of liver and left hemidiaphragm. At the end of the operation and before withdrawing the first trocar, 100ml normal saline in Group I and 1 mg/kg of ropivacaine in 100 ml normal saline in Group D will be sprayed on the upper surface of right and left lobe of liver and left hemidiaphragm in Group D. This is one off treatment.
Locations(1)
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ACTRN12609000948291