Not Yet RecruitingPhase 1ACTRN12609001014246

Treatment of acute pain after shingles with vitamin D cream

Treatment of acute herpes zoster neuralgia with high potency vitamin D cream


Sponsor

Jim Bartley

Enrollment

10 participants

Start Date

Jan 1, 2010

Study Type

Interventional

Conditions

Summary

Vitamin D is able to treat viral infections. As such a high potency vitamin D cream could also be useful in the treatment of the acute viral reactivation associated with acute herpes zoster. Inflammation of cells called glial and schwann cells which surround nerves in our nervous system are also known to have a major influence on pain. Drugs that reduce inflammation in these cells are now being trialled in a number of pain conditions. One drug/ natural supplement that offers particular promise is vitamin D. Because post herpetic neuralgia responds to a number of topical medications, vitamin D is being trialled in a topical form. If a vitamin D cream was an effective treatment for acute post herpetic neuralgia this would be a major treatment advance as it could provide a simple cost effective treatment option with minimal side effects.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 80 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether applying a vitamin D cream to the skin can relieve acute nerve pain caused by shingles. Adults aged 18 to 80 who are currently experiencing shingles-related pain and can apply the cream themselves may participate.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Use of a topical high potency vitamin D cream (20,000IU/g). a. Dose 20,000IU b. Twice a day c. Until pain resolves or for up to 4 weeks

Use of a topical high potency vitamin D cream (20,000IU/g). a. Dose 20,000IU b. Twice a day c. Until pain resolves or for up to 4 weeks


Locations(1)

New Zealand

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ACTRN12609001014246