Treatment of acute pain after shingles with vitamin D cream
Treatment of acute herpes zoster neuralgia with high potency vitamin D cream
Jim Bartley
10 participants
Jan 1, 2010
Interventional
Conditions
Summary
Vitamin D is able to treat viral infections. As such a high potency vitamin D cream could also be useful in the treatment of the acute viral reactivation associated with acute herpes zoster. Inflammation of cells called glial and schwann cells which surround nerves in our nervous system are also known to have a major influence on pain. Drugs that reduce inflammation in these cells are now being trialled in a number of pain conditions. One drug/ natural supplement that offers particular promise is vitamin D. Because post herpetic neuralgia responds to a number of topical medications, vitamin D is being trialled in a topical form. If a vitamin D cream was an effective treatment for acute post herpetic neuralgia this would be a major treatment advance as it could provide a simple cost effective treatment option with minimal side effects.
Eligibility
Inclusion Criteria3
- Age 18-80
- Adults with acute herpetic neuralgia
- Able to provide informed consent
Exclusion Criteria3
- Unable to apply vitamin D cream
- Skin condition or skin allergy so unable to use cream
- Unable to provide informed consent
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Interventions
Use of a topical high potency vitamin D cream (20,000IU/g). a. Dose 20,000IU b. Twice a day c. Until pain resolves or for up to 4 weeks
Locations(1)
View Full Details on ANZCTR
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ACTRN12609001014246