TerminatedPhase 3ACTRN12609001020279

The Exelon Patch (Transdermal Rivastigmine) for the treatment of severe delirium in elderly subacute care inpatients

A double blinded randomised placebo controlled trial of the exelon patch (transdermal rivastigmine) for the treatment of severe delirium in elderly subacute care inpatients.


Sponsor

Melbourne Health

Enrollment

60 participants

Start Date

Feb 7, 2010

Study Type

Interventional

Conditions

Summary

Acetylcholine levels are decreased in delirium, a condition of a sudden change in mental capacity occurring due to a illness, medication or similar insult. Rivastigmine is a medication for Alzhiemer's Disease, another condition where there is a change in mental capacity and low levels of acetylcholine. It increases levels of acetylcholine in the brain. THis trial aims to determine if a rivastigmine patch given to elderly patients in hospital after their illness has resolved but who still have delirium will have a less severe delirium.


Eligibility

Sex: Both males and femalesMin Age: 65 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether a rivastigmine skin patch (commonly used for dementia) can help treat severe delirium or confusion in elderly hospital patients. Adults aged 65 and over with severe delirium who are expected to remain in care for at least 2 weeks may be eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Transdermal Rivastigmine 4.6mg/hour patch applied topically changed daily for two weeks.

Transdermal Rivastigmine 4.6mg/hour patch applied topically changed daily for two weeks.


Locations(1)

Australia

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ACTRN12609001020279