The effect of propofol on emergence delirium in children after sevoflurane anaesthesia
The effect of propofol on emergence delirium in children after sevoflurane anaesthesia for magnetic resonance imaging (MRI). A randomized controlled trial.
Women's and Children's Hospital
250 participants
Jan 12, 2010
Interventional
Conditions
Summary
After anaesthesia children frquently become irritable and distressed. This is termed Emergence Delirium (ED). Sometimes this can lead to intravenous lines and surgical drains becoming dislodged. The child rarely remember this period and it rarely has any longterm consequences. A number of studies have suggested that a commonly used anaesthetic drug called propofol can be used to reduce the chance of this happening. We plan to administer a dose of propofol at the end of an anaesthetic to see whether it will reduce the rate of ED.
Eligibility
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Interventions
We wish to examine whether administration of intravenous propofol 3mg/kg over 3 minutes at the end of a sevoflurane anaesthetic can reduce the incidence of emergence delirium in children.
Locations(1)
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ACTRN12610000025033