Impact of topical lignocaine on the incidence of perioperative respiratory complications in children undergoing laryngo-tracheo-bronchoscopies – a double blind randomised controlled pilot study
Prof Britta Regli-von Ungern-Sternberg
200 participants
Nov 18, 2009
Interventional
Conditions
Summary
the purpose of this study is to characterize the modification induced by lignocaine on the incidence of intraoperative and postoperative respiratory complications in children undergoing laryngo tracheo bronchoscopies.
Eligibility
Inclusion Criteria1
- Children, aged 0 to 16 years, male or female undergoing an laryngo-tracheo-bronchoscopy (LTB).
Exclusion Criteria1
- Hypersensitivity to lignocaine, airway reconstruction surgery
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Interventions
Topical lignocaine vs. placebo onto vocal cords for a laryngo-tracheo-bronchoscopy. The lignocaine is applied directly following induction of anaesthesia. It is only applied once which takes one spray of lignocaine of 5-10 seconds duration. The lignocaine dose used will be a maximum of 4 mg/kg as topical spray (under vision) onto the vocal cords. For this trial, lignocaine 4% will be used in all children. In children > 30 kg 3 ml of lignocaine 4% will be applied.
Locations(1)
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ACTRN12610000235000