Postoperative sleep disturbances and quality of sleep after Remifentanil or Fentanyl –based anaesthesia
Postoperative sleep disturbances and quality of sleep after Remifentanil or Fentanyl –based anaesthesia in patients undergoing elective surgery
Manuel Wenk
100 participants
May 7, 2010
Interventional
Conditions
Summary
Modern anaesthesia incorporates the use of short-acting opioids such as remifentanil. Lately, there has been emerging evidence in the literature that some opioids might influence postoperative sleep quality for up to many months. We aim to compare sleep quality after exposure to 2 opioids regularly used in the clinical routine at Royal Perth Hospital.
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Interventions
Patients receive remifentanil-based anaesthesia during their elective operation. This is a one off treatment. Remifentanil is continuously infused intravenously at a rate of 0.15 - 0.3 mcg/kg/min. The infusion starts on induction of anaesthesia and finishes after the surgical procedure before emergence. Approximate duration of anaesthesia is between 45 and 120 minutes.
Locations(1)
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ACTRN12610000362099