Not Yet RecruitingPhase 4ACTRN12610000682044

Flucloxacillin in Cellulitis: A randomised controlled trial comparing continuous infusion to bolus dosing for uncomplicated cellulitis.

In an adult population with uncomplicated cellulitis presenting to an Emergency Department is flucloxacillin delivered by infusion comparable to bolus dosing for nursing workload and patient discharge at 24 hours?


Sponsor

Royal Brisbane & Women's Hospital

Enrollment

200 participants

Start Date

Oct 15, 2010

Study Type

Interventional

Conditions

Summary

The purpose of this study is to test the hypothesis that by managing Emergency Department patients with uncomplicated cellulitis in a short stay unit with a continuous 24 hour infusion of 8g of intravenous flucloxacillin as opposed to the current standard treatment of four 2g intravenous blouses administered every six hours for 24 hours, significant nursing time and resources would be saved with there being no decrease in the clinical or microbiological cure rate of the cellulitis.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 80 Yearss

Plain Language Summary

Simplified for easier understanding

This study compares two ways of giving the antibiotic flucloxacillin — continuous drip versus standard doses every few hours — to treat uncomplicated skin infections (cellulitis) in adults aged 18 to 80 managed in an emergency department short-stay unit.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Efficacy of 8g Flucloxacillin administered continuously via infusion over 24 hours

Efficacy of 8g Flucloxacillin administered continuously via infusion over 24 hours


Locations(1)

Australia

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