Does the perioperative use of Gabapentin reduce analgesia requirements in patients having delayed open reduction and internal fixation of forearm or ankle fractures?
Do patients who are having delayed open reduction and internal fixation of forearm or ankle fractures and who are given gabapentin peri-operatively, when compared with patients not given gabapentin, show lower narcotic analgesic requirements
Iain Salkield
50 participants
Nov 5, 2010
Interventional
Conditions
Summary
Gabapentin is a drug that is officially used to treat chronic pain. This study looks at whether it can help with the more acute pain from having broken bones in the wrist or ankle repaired with screws and plates. This is very painful for a relatively short period and if we find that gabapentin can help with this pain then this could become part of normal treatment.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Pre-operative and post-operative treatment with gabapentin for 24 hours. Preoperative dose would normally be 600 mg orally 30 minutes prior to surgery with 300 mg being given orally 8 hourly for 24 hours following completion of surgery. The doses would need to be reduced if a patient with moderate or worse renal failure was recruited.
Locations(1)
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ACTRN12610000848000