Are the intraperitoneal ropivacaine instillation and ropivacaine infiltration at the port site effective in relieving the postoperative pain after laparoscopic cholecystectomy?
In patients undergoing laparoscopic cholecystectomy, are intraperitoneal ropivacaine instillation and ropivacaine infiltration at the port site effective in terms of visceral pain, parietal pain, and shoulder tip pain?
Chung-Ang University
80 participants
May 1, 2008
Interventional
Conditions
Summary
The parietal component is incisional pain experienced at the port sites and visceral component is deep intra-abdominal pain related to diaphragmatic irritation caused by pnemoperitoneum and postcholecystectomy wound. Shoulder tip pain is presumably referred pain related to distension of diaphragm caused by pneumoperitoneum and resultant phrenic nerve neuropraxia.The aim of our prospective, randomized, double-blind study was to evaluate the intensity of visceral, parietal and shoulder tip pain, and to determine the efficacy of peritrocal injection and intraperitoneal instillation of ropivacaine on each pain.
Eligibility
Inclusion Criteria1
- patients undergoin laparscopic cholecystectomy
Exclusion Criteria1
- body weight lower than 45 kg or greater than 100 kg, history of severe underlying cardiovascular, pulmonary, renal or hepatic disease, or allergy to local anaesthetics
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Interventions
arm 1:both infiltration at the port site and intraperitoneal instillation: 20ml of a solution containing ropivacaine (2 mg/ml) was infiltrated at the port site before insertion of trocar and 100 ml of ropivacaine solution (2 mg/kg) was infused intraperitoneally immediately after the creation of the pneumoperitoneum and 10 min before the beginning of surgery.. arm 2: intraperitoneal instillation: 20ml normal saline was infiltrated at the port site before insertion of trocar, and 100 ml of ropivacaine solution (2 mg/kg) was infused intraperitoneally immediately after the creation of the pneumoperitoneum and 10 min before the beginning of surgery.. arm 3: infiltration at the port site:20ml of a solution containing ropivacaine (2 mg/ml) was infiltrated at the port site before insertion of trocar and 100 ml of normal saline solution was infused intraperitoneally immediately after the creation of the pneumoperitoneum and 10 min before the beginning of surgery..
Locations(1)
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ACTRN12610000910000