Comparison of different medications for the control of pain after tonsils and adenoid surgery.
Comparative, prospective, and randomized study of tonsillectomy/adenotonsillectomy post-operative pain control in children.
Edwin Tamashiro
100 participants
Dec 1, 2010
Interventional
Conditions
Summary
Tonsillectomy and Adenotonsillectomy are the main surgeries performed in children worlwide. However, there is no consensus on how is the best way to manage pain after surgery in these cases. In this study, our primary goal will be to investigate if the additional use of antibiotics (amoxicilin), non-esteroidal antiinflammatory (ibuprofen) or corticosteroid (prednisolone) can change the history of pain that follows these surgeries. Additionally, we will also investigate if the use of these drugs in the post-operative period leads to adverse effects. Finally, we will balance the risk/benefit use of these drugs in the post-operative time of tonsillectomy/adenotonsillectomy in children.
Eligibility
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Interventions
During the 7 days after tonsillectomy/adenotonsillectomy, children between 4-10 years will receive either analgesic alone as necessary (dipyrone - 20mg/kg/dose - or acetaminofen - 15mg/kg/dose, up to 4 times a day, oral drops) or analgesics combined with amoxicilin (50mg/kg/day, 3 times a day for 7 days, oral suspension), prednisolone (0.5mg/kg/day once a day for 7 days, oral solution), ibuprofen (15mg/kg/day, divided in 3 times a day for 7 days, oral drops) or amoxicilin+prednisolone for 7 days.
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ACTRN12610001084077