Not Yet RecruitingPhase 4ACTRN12611000050954

Comparison of hemodynamic parameters of isoflurane and sevoflurane during lowflow controlled anesthesia

Comparison of hemodynamic parameters between low flow Isoflurane and low flow Sevoflurane anesthesia during controlled ventilation with Laryngeal Mask Airway


Sponsor

Tabriz University of Medical Sciences

Enrollment

80 participants

Start Date

Feb 1, 2011

Study Type

Interventional

Conditions

Summary

Laryngeal Mask Airway(LMA) is a good device for airway management which is used routinly in operating room nowadays.Low flow anesthesia is almost a new concept in maintenance of anesthesia which leads to better control of airway temperature and humidity with stable hemodynamic. Previous studies showed that we can use isoflurane with controlled low flow anesthesia during operation. Sevoflurane is a new anesthetic which has some priorities to other anesthetics. But there are some concerns about its use during contooled low flow anesthesia with LMA. 80 patients will be enrolled in this study. Patients will be randomized to two 40 patient groups. In one group anesthesia will be maintained with isoflurane and in the other group will be maintained by sevoflurane. All patients will be ventilated through LMA with low flow anesthesia. Hemodynamic Parameters will be noted during anestheia for each person.


Eligibility

Sex: Both males and femalesMin Age: 20 YearssMax Age: 60 Yearss

Plain Language Summary

Simplified for easier understanding

This study compares two commonly used anaesthetic gases (isoflurane and sevoflurane) to see how they affect blood pressure, heart rate, and other vital signs during surgery in healthy adults aged 20 to 60. The goal is to determine which gas provides more stable conditions during low-flow anaesthesia.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

maintenance of low flow Anestheia with volume controlled ventilation through Laryngeal Mask Airway(LMA)with sevoflurane(Inhaled anesthetic) with 2-2.5% in initial phase(10 minutes) and after that main

maintenance of low flow Anestheia with volume controlled ventilation through Laryngeal Mask Airway(LMA)with sevoflurane(Inhaled anesthetic) with 2-2.5% in initial phase(10 minutes) and after that maintained on 3-3.5% till we reach near the time of ending operation., at first we set fresh gas flow at 6 lit/min and after that the fresh gas flow decreases to 1lit/min during 10-15 minutes. hemodynamic parameters will be monitored.


Locations(1)

East Azerbaijan, Iran, Islamic Republic Of

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ACTRN12611000050954