RecruitingPhase 4ACTRN12611000385943

Effect of Propofol on Ability to Drive

Estimation of the simulated driving ability of post-surgical patients with varying Propofol plasma concentrations


Sponsor

Monash Medical Centre

Enrollment

20 participants

Start Date

Jun 14, 2011

Study Type

Interventional

Conditions


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at how propofol — a commonly used anaesthetic drug — affects a person's ability to drive after day surgery. Some patients feel they are ready to drive sooner than they actually are after an anaesthetic. The study uses a driving simulator test to measure reaction time and driving performance before and after surgery to find out how long people should wait before getting behind the wheel. You may be eligible if: - You are 18 years or older - You are having day surgery at Monash Medical Centre - You are expected to receive a propofol-based anaesthetic - You hold a current driver's licence You may NOT be eligible if: - You are under 18 - You do not speak enough English to understand the consent form - You are too unwell to participate in the study - You are allergic to propofol - You have had a stroke or have a brain tumour - You do not have a current driver's licence - You are missing a limb Talk to your doctor about whether this trial might be right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Administration of Propofol via intravenous infusion a) The dose will be titrated to achieve an estimated plasma concentration of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 mg/mL in stepwise progression b) the inf

Administration of Propofol via intravenous infusion a) The dose will be titrated to achieve an estimated plasma concentration of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 mg/mL in stepwise progression b) the infusion will be continuous and will not exceed 30 minutes


Locations(1)

Australia

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ACTRN12611000385943