Vitamin D status in heart surgery patients and effects on clinical outcomes
In elective cardiac surgery patients, what is the effect of vitamin D status on clinical ICU outcomes, and does a 6 week period of vitamin D supplementation post surgery increase serum vitamin D levels in those found to be deficient?
The Alfred
100 participants
Jul 1, 2011
Interventional
Conditions
Summary
Vitamin D deficiency and insufficiency has been detected in the general community and is likely to be present in cardiac intensive care unit patients. This may impact recovery from surgery and rehospitalisation risk. The primary aim of this study is to identify the prevalence of vitamin D deficiency and insufficiency in cardiac ICU patients presenting to the Alfred Hospital. Secondary aims are to identify whether vitamin D deficiency or insufficiency is associated with longer ICU stay, longer ventilation time and/or APACHE 3 scores showing deterioration. And also to ascertain whether supplementation with 4000IU of vitamin D daily restores serum levels to within normal range.
Eligibility
Plain Language Summary
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Interventions
After initial screening before surgery, participants found to be deficient in vitamin D will be given oral supplements of 4000IU of vitamin D3 daily for 6 weeks after discharge from hospital.
Locations(1)
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ACTRN12611000516987