CompletedPhase 2ACTRN12611000581965

Aged garlic extract for uncontrolled hypertension: a dose-response trial

Aged garlic extract or placebo for uncontrolled hypertension: a randomised double-blind parallel dose response trial

Sponsor

Dr Karin Ried

Enrollment

84 participants

Start Date

Aug 1, 2011

Study Type

Interventional

Conditions

treated uncontrolled hypertension

Summary

The study will investigate the efficacy, dose-reponse relationship and acceptability of aged garlic extract for reducing blood pressure in treated but uncontrolled hypertensive general practice patients.

Eligibility

Sex: Both males and femalesMin Age: 20 YearssMax Age: 80 Yearss

Plain Language Summary

Simplified for easier understanding

This trial tests different doses of aged garlic extract to see if it can lower blood pressure in people whose hypertension is not fully controlled by medication. Participants must be aged 20 to 80 with systolic blood pressure above 140 mmHg and already on blood pressure medication for at least 2 months.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Active groups: Aged garlic extract (AGE, Kyolic) orally daily for 12 weeks Group 1: 4 capsules containing 960 mg AGE, 2.4 mg S-AllylCysteine (SAC) Group 2: 2 capsules containing 480 mg AGE, 1.2 mg S

Active groups: Aged garlic extract (AGE, Kyolic) orally daily for 12 weeks Group 1: 4 capsules containing 960 mg AGE, 2.4 mg S-AllylCysteine (SAC) Group 2: 2 capsules containing 480 mg AGE, 1.2 mg SAC Group 3: 1 capsule containing 240 mg AGE, 0.6 mg SAC

Locations(1)

SA, Australia

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ACTRN12611000581965