Aged garlic extract for uncontrolled hypertension: a dose-response trial
Aged garlic extract or placebo for uncontrolled hypertension: a randomised double-blind parallel dose response trial
Dr Karin Ried
84 participants
Aug 1, 2011
Interventional
Conditions
Summary
The study will investigate the efficacy, dose-reponse relationship and acceptability of aged garlic extract for reducing blood pressure in treated but uncontrolled hypertensive general practice patients.
Eligibility
Inclusion Criteria1
- Blood pressure > 140 mm Hg systolic under trial conditions; on established plan of BP medication (one or more classes) for at least 2 months
Exclusion Criteria1
- Unable to give informed consent; unstable medical conditions or serious illness; severe hypertension (> 180 mm Hg); already taking daily garlic supplements
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Interventions
Active groups: Aged garlic extract (AGE, Kyolic) orally daily for 12 weeks Group 1: 4 capsules containing 960 mg AGE, 2.4 mg S-AllylCysteine (SAC) Group 2: 2 capsules containing 480 mg AGE, 1.2 mg SAC Group 3: 1 capsule containing 240 mg AGE, 0.6 mg SAC
Locations(1)
View Full Details on ANZCTR
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ACTRN12611000581965