Not Yet RecruitingPhase 4ACTRN12611000589987

Randomised placebo controlled trial of inhaled corticosteroids for treatment of acute and chronic cough in children.

Is a two week course of inhaled corticosteroids efficacious as primary treatment of cough in children, compared to standard therapy?


Sponsor

Prof Anne Chang

Enrollment

161 participants

Start Date

Jun 8, 2011

Study Type

Interventional

Conditions

Summary

This study will help us answer the question: Should children with acute or chronic cough be given inhaled corticosteroids to promote faster recovery and improve ability for children to return to their normal daily routines? This study will also look at what viruses may be contributing to cough in children and how cough impacts on the quality of life of children and their families.


Eligibility

Sex: Both males and femalesMin Age: 2 YearssMax Age: 16 Yearss

Plain Language Summary

Simplified for easier understanding

This trial tests whether inhaled corticosteroids can effectively treat acute or chronic cough in children aged 2 to 16. It is a placebo-controlled study, meaning some children receive the active medication while others receive an inactive inhaler. Children who recently used corticosteroids, have chronic respiratory illness, or are immunocompromised are not eligible.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Participants will be randomised to receive either inhaled corticosteroids or placebo. Participants allocated to the intervention group will receive 250 micrograms fluticasone propionate twice daily fo

Participants will be randomised to receive either inhaled corticosteroids or placebo. Participants allocated to the intervention group will receive 250 micrograms fluticasone propionate twice daily for two weeks, delivered via metered dose inhaler and spacer (with or without mask, depending on age and technique).


Locations(1)

Australia

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ACTRN12611000589987