NSW Cancer Lifestyle and Evaluation of Risk Study (CLEAR Study)

The NSW Cancer, Lifestyle, and the Evaluation of Risk (CLEAR) Study is a multi-centre case-control surveillance study in the NSW population. The objectives of the study are: 1. To provide ongoing data on the relative importance of known or emerging exposures and their relationships to leading or emerging cancer types. 2. To investigate in the short term once sample sizes permit, the effects of migration, ethnicity, physical activity, alcohol consumption, smoking, reproductive history, occupation, screening behaviour and certain dietary patterns on the risk of developing cancer of the colon and rectum, prostate, breast and lung, cutaneous melanoma and non-Hodgkin lymphoma. 3. To investigate in the longer term, once sample sizes permit, the effects of these factors on rarer cancer types, such as hepatoma, thyroid, ovarian and pancreatic cancers. 4. To develop a recruitment infrastructure and biological repository of sufficient size to enable the testing of new hypotheses on gene and environment factors, and in some situations, gene-environment interactions, on the risk of cancers affecting the Australian population.