CompletedPhase 1ACTRN12611000771954

Nutrition supplementation and immunity in athletes

Effects of butyrylated high amylose maize starch compared to low amylose maize starch on faecal microbiology and immunity in athletes.


Sponsor

Australian Institute of Sport

Enrollment

40 participants

Start Date

Oct 20, 2008

Study Type

Interventional

Conditions

Summary

This study will investigate 28 days of butyrylated resistant starch supplementation on faecal short chain fatty acids, faecal microbiology and immunity in well trained athletes. Well trained athletes undertaking prolonged endurance exercise suffer gastrointestinal dysfunction and suppression of immunity from heavy exercise training. This supplement is being investigated to examine whether it may reverse these issues.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 50 Yearss

Plain Language Summary

Simplified for easier understanding

This study examines whether a nutritional supplement can boost immune function in trained athletes aged 18-50. Participants must have at least 3 years of athletic training and meet minimum fitness thresholds, and researchers will measure immune markers to see if supplementation helps prevent illness during intense training.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

To examine the effect of butyrylated high amylose maize starch on immune and microbiological parameters in 40 well trained athletes in a double blind placebo controlled parallel trial over 28 days. Bu

To examine the effect of butyrylated high amylose maize starch on immune and microbiological parameters in 40 well trained athletes in a double blind placebo controlled parallel trial over 28 days. Butyrylated high amylose maize starch is non-digestible starch that promotes the growth of beneficial microbes in the gastrointestinal tract. In this case the starch has had butyric acid incorporated into its structure. Butyric acid is the primary fuel for colonocytes and promotes normal functioning of these cells. The supplement is in a powder form and will be mixed and consumed with a protein drink (musashi protein powder) twice daily for 28 days. A total of 40 grams per day of the butyrylated high amylose maize starch will be consumed per day. The expected outcomes are an increase in faecal short chain fatty acids (butyrate, acetate and propionate), an increase in total faecal bacteria and increases in salivary antimicrobial proteins and serum cytokines.


Locations(1)

Australia

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ACTRN12611000771954