Can certain anaesthesia medications & techniques provide additional benefits after cancer surgery apart from pain relief and speed of recovery from that surgery (LIPO trial - Lignocaine infusion given peri-operatively)
Can anaesthetic technique in the form of peri-operative lignocaine infusion to blunt surgical stress response have additional benefits in long term outcome following primary cancer surgery
Palmerston North Hospital
600 participants
Oct 1, 2011
Interventional
Conditions
Eligibility
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Interventions
Intra-operative lignocaine infusion. Replica of methodology from existing study, specifically Kuo et al, British Journal of Anaesthesia, 97 (5): 640–6 (2006): 2mg/kg over 15 mins, followed by 3mg/kg/hr IV. Continued intra-op and 30 mins post op. Intraoperative top-up fentanyl and post operative morphine patient controlled analgesia (PCA) if required. Additional resource [ANZCTR no: 12609001073291] & Annals of Surgery - Volume 246, Number 2, August 2007 page 192 - slight modification in methodology & dose
Locations(1)
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ACTRN12611001005943