CompletedPhase 4ACTRN12611001059954

Granisetron and incidence of shivering in children after spinal anesthesia

Premedication with Granisetron prevents shivering during spinal anaesthesia in children

Sponsor

Yasser M. Amr

Enrollment

80 participants

Start Date

May 1, 2011

Study Type

Interventional

Conditions

shivering during spinal anesthesia in children

Summary

80 children aged from 2-5 years scheduled for surgery in lower limb were prepared for spinal anesthesia. Children were classified into two groups, Group 1 (40 children) received intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% and Group 2 (40 children) received intravenous 10 ml 0.9% saline to be given over 5 minutes just before spinal puncture. Shivering, core temperature levels of motor and sensory block were assessed.

Eligibility

Sex: Both males and femalesMin Age: 2 YearssMax Age: 5 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether the anti-nausea medication granisetron can prevent shivering in young children (aged 2-5) undergoing lower limb surgery with spinal anesthesia. Shivering is a common side effect of spinal anesthesia, and this trial evaluates a potential preventive treatment.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Effect of Premedication with Granisetron on incidence of shivering during spinal anesthesia in children intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% to be given over 5 minutes just

Effect of Premedication with Granisetron on incidence of shivering during spinal anesthesia in children intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% to be given over 5 minutes just before spinal puncture. Spinal block was done by intrathecal hyperbaric bupivacine 0.5% (0.5 mg/Kg).

Locations(1)

Egypt

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ACTRN12611001059954