CompletedPhase 4ACTRN12611001059954

Granisetron and incidence of shivering in children after spinal anesthesia

Premedication with Granisetron prevents shivering during spinal anaesthesia in children


Sponsor

Yasser M. Amr

Enrollment

80 participants

Start Date

May 1, 2011

Study Type

Interventional

Conditions

Summary

80 children aged from 2-5 years scheduled for surgery in lower limb were prepared for spinal anesthesia. Children were classified into two groups, Group 1 (40 children) received intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% and Group 2 (40 children) received intravenous 10 ml 0.9% saline to be given over 5 minutes just before spinal puncture. Shivering, core temperature levels of motor and sensory block were assessed.


Eligibility

Sex: Both males and femalesMin Age: 2 YearssMax Age: 5 Yearss

Inclusion Criteria1

  • children ASA 1 and 2 scheduled for lower limb surgery under spinal anaesthesia were entered into study

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Interventions

Effect of Premedication with Granisetron on incidence of shivering during spinal anesthesia in children intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% to be given over 5 minutes just

Effect of Premedication with Granisetron on incidence of shivering during spinal anesthesia in children intravenous 10 mcg/Kg granisetron diluted in 10 ml saline 0.9% to be given over 5 minutes just before spinal puncture. Spinal block was done by intrathecal hyperbaric bupivacine 0.5% (0.5 mg/Kg).


Locations(1)

Egypt

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ACTRN12611001059954