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RecruitingACTRN12611001157965

High vs low urine output targets in surgical patients.

High vs. Low Urine Output Targets in Surgical Patients: a randomised assessor-blinded safety study.

Sponsor

The University of Auckland

Enrollment

40 participants

Start Date

Nov 28, 2011

Study Type

Interventional

Conditions

Major bowel surgery

Summary

This is a randomised controlled trial comparing a low urine output target to a high urine output target in the context of bowel resection.

Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 85 Yearss

Inclusion Criteria1

  • Patients undergoing elective bowel resection

Exclusion Criteria1

  • Preexisting kidney disease or damage, perioperative nephrotoxic substance administration, pre-existing hepatic failure, ASA class IV, morbid obesity, pregnant or lactating females.

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Interventions

For the first 48 hours from the start of surgery, participants undergoing elective bowel resection will have their perioperative fluid management guided by a urine output target of 0.2 ml/kg/h. If a p

For the first 48 hours from the start of surgery, participants undergoing elective bowel resection will have their perioperative fluid management guided by a urine output target of 0.2 ml/kg/h. If a particpant's urine output falls below this limit, they will bolused with 500mls of intravenous fluid over 15 minutes to raise their urine output above the required target. Their urine output will be checked hourly and the processed repeated should it fall below the required target.

Locations(1)

New Zealand

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ACTRN12611001157965