RecruitingPhase 4ACTRN12611001166965

Comparison of dexamethasone route of administration on ankle block duration and analgesia for foot and ankle surgery


Sponsor

Ms Rachel Dawson

Enrollment

90 participants

Start Date

Jan 2, 2012

Study Type

Interventional

Conditions

Summary

Post operative pain following ankle and foot surgery is troublesome. It is common practice for regional anaesthetic blockade to be used to prolong post operative pain relief for about 14 hours. Dexamethasone has been shown to prolong regional blockade in the upper limb, but this has not been investigated in the lower limb. The optimal route of administration for dexamethasone has not been investigated and it is unknown whether there is advantage to administering dexamethasone intravenously, or mixed with the block. We aim to investigate whether dexamethasone can prolong regional anaesthesia in the lower limb and determine if there are differences in effect when administered intravenously compared with when it is added to the block.


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding the steroid dexamethasone — either injected into the nerve block or given through a vein — can make pain relief last longer after foot surgery. Patients having an ankle nerve block (a type of regional anesthesia) for elective foot surgery will be randomly assigned to one of three groups. Researchers want to find out if dexamethasone extends the block and which route of giving it works best. You may be eligible if: - You are 18 years or older - You are having elective metatarsal osteotomy foot surgery - Your general health is good to moderate (ASA score 1–3) You may NOT be eligible if: - You are allergic to the local anesthetic (ropivacaine) or dexamethasone - You have poorly controlled diabetes or pre-existing nerve damage in the foot - You take high-dose steroids regularly or strong opioid pain medications - You are pregnant or have active peptic ulcer disease - You cannot understand English Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Patients undergoing elective ankle or foot surgery will receive an ultrasound guided ankle/foot block and be randomly allocated to one of three groups: Arm 1 The intravenous dexamethasone group w

Patients undergoing elective ankle or foot surgery will receive an ultrasound guided ankle/foot block and be randomly allocated to one of three groups: Arm 1 The intravenous dexamethasone group will receive 8 mg (2 ml) dexamethasone intravenously and 2 ml saline added to the ropivacaine ankle block. Arm 2 The ankle block dexamethasone group will receive 8 mg (2 ml) dexamethasone added into the ropivacaine ankle block and 2 ml saline intravenously.


Locations(1)

Australia

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ACTRN12611001166965