RecruitingPhase 4ACTRN12612000007831

The effect of intravenous lidocaine infusion on the pain after laparoscopic assisted distal gastrectomy

In patients undergoing laparoscopic assisted distal gastrectomy, is intravenous lidocaine infusion effective in reducing post-operative pain?


Sponsor

Chung-Ang University

Enrollment

36 participants

Start Date

Mar 1, 2011

Study Type

Interventional

Conditions

Summary

Intravenous lidocaine infusion in various type of surgery is known to effective in reducing post-operative pain, analgesic requirements, the stress response and lengthens the period to first post-operative analgesic requirement. We hypothesized that intravenous lidocaine infusion reduce the pain after laparoscopic surgery. Therefore we performed a study to investigate the effectiveness of lidocaine on pain after laparoscopic assisted distal gastrectomy. .


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Inclusion Criteria1

  • patients undergoin laparoscopic assisted distal gastrectomy

Exclusion Criteria1

  • body weight lower than 45 kg or greater than 100 kg, history of severe underlying cardiovascular, pulmonary, renal or hepatic disease, or allergy to local anaesthetics

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Interventions

Intravenous (IV) lidocaine infusion:group: IV administration of 1mg/ml lidocaine was performed 2 minute before orotracheal intubation. Patients in arm1 received an IV bolus injection of lidocaine (1.

Intravenous (IV) lidocaine infusion:group: IV administration of 1mg/ml lidocaine was performed 2 minute before orotracheal intubation. Patients in arm1 received an IV bolus injection of lidocaine (1.5 mg/kg) followed by a continuous IV infusion of lidocaine at 2 mg/kg/hr during the operation (150-180 min).


Locations(1)

Korea, Republic Of

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ACTRN12612000007831