RecruitingPhase 4ACTRN12612000007831

The effect of intravenous lidocaine infusion on the pain after laparoscopic assisted distal gastrectomy

In patients undergoing laparoscopic assisted distal gastrectomy, is intravenous lidocaine infusion effective in reducing post-operative pain?


Sponsor

Chung-Ang University

Enrollment

36 participants

Start Date

Mar 1, 2011

Study Type

Interventional

Conditions

Summary

Intravenous lidocaine infusion in various type of surgery is known to effective in reducing post-operative pain, analgesic requirements, the stress response and lengthens the period to first post-operative analgesic requirement. We hypothesized that intravenous lidocaine infusion reduce the pain after laparoscopic surgery. Therefore we performed a study to investigate the effectiveness of lidocaine on pain after laparoscopic assisted distal gastrectomy. .


Eligibility

Sex: Both males and femalesMin Age: 18 Yearss

Plain Language Summary

Simplified for easier understanding

This study tests whether giving a continuous intravenous (IV) drip of lidocaine (a local anaesthetic) during and after laparoscopic stomach surgery (laparoscopic assisted distal gastrectomy) reduces post-operative pain. Previous research has shown lidocaine infusions can reduce pain, painkiller needs, and stress responses after various types of surgery. Researchers want to find out if this also works for stomach surgery. You may be eligible if: - You are 18 years or older - You are scheduled to have a laparoscopic assisted distal gastrectomy (removal of part of the stomach using keyhole surgery) You may NOT be eligible if: - You weigh less than 45 kg or more than 100 kg - You have a history of severe cardiovascular, lung, kidney, or liver disease - You have an allergy to local anaesthetic medications Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Intravenous (IV) lidocaine infusion:group: IV administration of 1mg/ml lidocaine was performed 2 minute before orotracheal intubation. Patients in arm1 received an IV bolus injection of lidocaine (1.

Intravenous (IV) lidocaine infusion:group: IV administration of 1mg/ml lidocaine was performed 2 minute before orotracheal intubation. Patients in arm1 received an IV bolus injection of lidocaine (1.5 mg/kg) followed by a continuous IV infusion of lidocaine at 2 mg/kg/hr during the operation (150-180 min).


Locations(1)

Korea, Republic Of

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ACTRN12612000007831