Prostaglandin gel versus oxytocin for induction of labour in term prelabour rupture of membranes
For women with term prelabour rupture of membranes who wish active management does use of PG gel result in better satisfaction and less need for oxytocin without increasing risk of neonatal sepsis.
ipswich Hospital
280 participants
Feb 1, 2009
Interventional
Conditions
Summary
Term PROM is a common problem. Women have traditionally been offered oxytocin infusion. This requires intravenous fluids, continuous FHR monitoring and the woman is restricted to bed. PG gel has been shown in a large RCT to be safe and effective but has not become widely used in the public sector. This study will address safety and efficacy as well as womens satisfaction of the two methods of induction.
Eligibility
Inclusion Criteria6
- gestational age >36 weeks and 6 days
- Confirmed SROM
- Singleton pregnancy
- live fetus
- cephalic presentation
- informed consent
Exclusion Criteria6
- severe medical problem
- compromised fetus
- indication for immediate delivery
- suspected sepsis
- previous c/section
- known gbs infection
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Interventions
Three doses of Prostaglandin F2 alpha gel 6 hours apart = first dose after obtaining consent doses are 2mg each time for nulliparous women and 1mg initially and then 2 mg for multiparous women gel will be inserted vaginally
Locations(1)
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ACTRN12612000093886