Novel Treatment of Phobias in Children and Teenagers

This study is testing whether a medication called D-Cycloserine can make a single session of exposure therapy work better for children and teenagers with a specific phobia (an intense fear of something like heights, animals, or needles). D-Cycloserine is normally an antibiotic for tuberculosis, but research has shown it may help the brain learn to be less afraid. The study involves one session of guided exposure to the feared object or situation, with participants receiving either the study drug or a placebo pill. You may be eligible if: - You are between 7 and 17 years old - You have been diagnosed with a specific phobia - You have an anxiety disorder as your primary diagnosis - If you are already on an SSRI medication, the dose has been stable for at least one month You may NOT be eligible if: - You have an organic brain condition, psychosis, or pervasive developmental disorder - You have a history of seizures - You are pregnant or sexually active without using birth control - You are currently receiving other psychotherapy - You have active tuberculosis or are taking medication that lowers the seizure threshold (such as clozapine) - You have a significant medical condition affecting the heart, liver, kidneys, or lungs - You have a low IQ (below approximately 70) Talk to your doctor about whether this trial might be right for you.