The effect of intravenous lidocaine infusion on the pain after subtotal gastrectomy
In patients undergoing subtotal gastrectomy, is intravenous lidocaine infusion effective in reducing post-operative pain?
Chung-Ang University
40 participants
Jun 1, 2012
Interventional
Conditions
Summary
Intravenous lidocaine infusion in various type of surgery is known to effective in reducing post-operative pain, analgesic requirements, the stress response and lengthens the period to first post-operative analgesic requirement. We hypothesized that intravenous lidocaine infusion reduce the pain after subtotal gastrectomy. Therefore we performed a study to investigate the effectiveness of lidocaine on pain after subtotal gastrectomy .
Eligibility
Inclusion Criteria1
- patients undergoing subtotal gastrectomy
Exclusion Criteria1
- body weight lower than 45 kg or greater than 100 kg, history of severe underlying cardiovascular, pulmonary, renal or hepatic disease, or allergy to local anaesthetics
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Interventions
Intravenous (IV) lidocaine infusion:group: IV administration of 1mg/ml lidocaine was performed 2 minute before orotracheal intubation. Patients in arm1 received an IV bolus injection of lidocaine (1.5 mg/kg) followed by a continuous IV infusion of lidocaine at 2 mg/kg/hr during the operation (150-180 min).
Locations(1)
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ACTRN12612000545864