Effects of preoperative oral carbohydrate solution intake on thermoregulation
Effects of preoperative oral carbohydrate solution intake on thermoregulation in female patients undergoing myomectomy-hysterectomy under general anesthesia
Ayse Belin OZER
40 participants
Mar 20, 2011
Interventional
Conditions
Summary
Background: Anesthesia practices is among practices that change heat regulation system and thus make patients lead to hypothermia. The aim of this study is to investigate the oral carbohydrate solution administered preoperatively on heat regulation system. Methods: The study included 40 female patients that were implemented general anesthesia. Patients were randomly divided into two groups: Group C (patients that stopped oral implementation 8 hours before the operation) and Group CH (800 ml oral carbohydrate fluid 8 hours before the operation and 400 ml oral carbohydrate fluid 2 hours before the operation). Patients were monitored as standard and temperature probes were placed. Heart rate, mean arterial pressure, and central and peripheral temperatures were recorded immediately before anesthetics induction, 5 minute intervals after the anesthetics induction, and in PACU every 10 minutes. Mean skin temperature, mean body temperature, and vasoconstriction threshold were estimated with the help of recorded temperatures. Results: A statistically significant difference was not observed between demographic data of patients. In general, a decrease in tympanic and mean body temperature following anesthetic administration in groups, and increase in mean skin temperature, and an increase were observed in all these three levels in recovery unit. Tympanic temperature was found to be significantly high at 25th, 55th, 65th, and 95th minutes before and after induction in Group C compared to Group CH. (p<0.05). Although mean skin temperature was found to be lower in Group C compared to Group CH in almost all periods, it was established that it did not have any significant difference in mean body temperature. In PACU, it was found that the tympanic temperature was higher in Group C compared to Group CH at the 60th minute (p<0.05). Postoperative shivering score was found to be significantly higher in Group C compared to Group CH (p<0.01). Vasoconstriction occurred at the 50th minute in Group C and 75th minute in Group CH. Vasoconstriction threshold was established to be 35.45 plus/minus 0.72 C degrees in Group C and 34.77 plus/minus 0.53 C degrees in Group CH. Conclusions: Oral carbohydrate solution administered in preoperative period was established to have effects (as decrease in tympanic temperature and vasoconstriction threshold) thought to be negative on tympanic temperature, vasoconstriction, and vasoconstriction threshold and to significantly decrease however the postoperative tremor.
Eligibility
Inclusion Criteria1
- The study included 40 female patients who were to undergo myomectomy-hysterectomy under general anesthesia with ages ranging between 18 and 50 year and that have I-II ASA physical status classification patients were chosen from among the cases to undergo operation between the hours 08:00 am and 13:00 pm.
Exclusion Criteria1
- Patients that had an inflammatory disease, diabetes mellitus, muscle diseases, hypo-hyperthyroidism, Parkinson disease, Raynaud phenomenon, with body mass index below 20 and above 30, used drug affecting body temperature (beta-blocker, calcium channel blocker, clonidine, steroid, antiepileptic, NSAI, benzodiazepine) and delayed gastric emptying (pregnancy, gastroesophageal reflux, opioid use) were excluded from the study. In addition, patients that will undergo an operation that takes less than 60 minutes or more than 180 minutes were not included in the study. Patients that had alterations in their hemodynamic parameters more than 30%, patients that required the use of vasopressor or vasodilator, and patients needed blood transfusion were excluded from the study.
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Interventions
Patients were randomly divided into two groups. Group C (control group, n=20): included patients who oral intake stopped 8 hours before operation and Group CH (preoperative carbohydrate group, n=20): patients that were administered oral carbohydrate fluid (12.6 %, 50 kcal per 100 ml fluid) prepared for preoperative period as 800 ml to be administered 8 hours before the operation and as 400 ml 2 hours before the operation.
Locations(1)
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ACTRN12612000792820