TerminatedPhase 3ACTRN12612000921886

dexamethasone and tramadol as additives to local anesthetics in ultrasound guided supraclavicular brachial plexus (SCBP) block and duration of analgesia.

The effect of tramadol or dexamethasone added to lidocaine for a ultrasound guided supraclavicular brachial plexus (SCBP) block on the onset, duration of sensory and motor blockade and first request of analgesia.


Sponsor

Tunisian Military Hospital

Enrollment

60 participants

Start Date

Sep 1, 2012

Study Type

Interventional

Conditions

Summary

During nerve blocks (which can control postoperative pain effectively), various drugs have been proposed in combination with local anesthetics (LA) to help reduce onset time and to prolong the duration of action and postoperative analgesia. Clonidine, epinephrine, and opioids are such examples but they are not without side effects. Tramadol and dexamethasone was proposed as safe adjuvents to LA but there were no study comparing those two molecules in ultrasound guided (US) peripheral nerve blocks.


Eligibility

Sex: Both males and femalesMin Age: 18 YearssMax Age: 80 Yearss

Inclusion Criteria1

  • patients undergoing upper limb wrist/hand/elbow or distal arm surgery

Exclusion Criteria1

  • history of lung disease, obesity (body mass index > 30 kg/m2), a history of chronic pain or psychiatric disorder, drug or alcohol abuse, and hypersensitivity to local anesthetics

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Interventions

15 ml lidocaine 2% + 8 mg dexamethasone in single shot ultrasound guided supraclavicular brachial plexus block.

15 ml lidocaine 2% + 8 mg dexamethasone in single shot ultrasound guided supraclavicular brachial plexus block.


Locations(1)

tunis, Tunisia

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ACTRN12612000921886