Inhaled verapamil in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease (COPD)

This study is testing whether verapamil — a medicine normally used for high blood pressure and heart rhythm problems — can also help lower high blood pressure in the lungs (pulmonary hypertension) when it is caused by COPD (a chronic lung disease). The medication is delivered as a mist inhaled through a nebulizer rather than a pill, which may allow it to work more directly in the lungs. You may be eligible if: - You have COPD with high pulmonary artery pressure (above 45 mmHg) - Your heart's pumping function (ejection fraction) is normal (above 40%) You may NOT be eligible if: - You are pregnant - You have had an allergic reaction to verapamil before - You have sepsis or a current infection - You have a second- or third-degree heart block or abnormal heart rhythm - You are currently having a COPD flare-up - You are already taking another calcium channel blocker, sildenafil, or bosentan - You have end-stage heart, kidney, or liver disease Talk to your doctor about whether this trial might be right for you.