Evaluating treatment efficacy of citalopram, symbiotic, and mebeverine for children with functional abdominal pain.

The objective of this study is to evaluate the effect of citalopram, mebeverine, and synbiotic on children functional abdominal pain. This study is randomized - placebo controlled trial. Children age 6 to 18 year old with functional abdominal pain will be assigned in to four groups of 50 person each. Group one: will receive citalopram 10 mg/day in first week and 20 mg/day for fallowing 3 weeks. Group2: children will take 270 mg/day mebeverine for four weeks. Group3: Children in this group will consume Lactol (300 million spores plus 200 mg FOS) for four weeks. In control group children take placebo for four weeks. Clinical Global Impression for severity (CGI-s) and Wang-Baker Faces pain Rating will be measured at the baseline and at the end of treatment (week four) and at the end of study (12weeks latter) also Clinical Global Impression for Improvement CGI-I will be measured at week four and week 12. patients will be followed up at week 2 by phone and at week four and 12 be interviewed and physical examination will be done to evaluate medical tolerance and drug side effects