RecruitingPhase 2ACTRN12613000170729
Open Label Extension Study to Evaluate the Safety, Tolerability and Cognitive Effects of VEL015 (Sodium Selenate) in Patients with Alzheimer’s Disease
Sponsor
Velacor Therapeutics Pty Ltd
Enrollment
40 participants
Start Date
Oct 30, 2012
Study Type
Interventional
Conditions
Summary
Open Label Extension Study to Evaluate the Safety, Tolerability and Cognitive Effects of VEL015 (Sodium Selenate) in Patients with Alzheimer’s Disease
Eligibility
Sex: Both males and femalesMin Age: 55 Yearss
Plain Language Summary
Simplified for easier understanding
This study is an extension of an earlier Alzheimer's disease trial that tested sodium selenate, a form of selenium that may slow disease progression by targeting a specific protein in the brain called tau. This extension study gives participants who completed the original trial the chance to continue receiving the drug and to be monitored for further safety and changes in memory and thinking.
You may be eligible if:
- You are 55 years of age or older
- You completed the previous Velacor 002 Alzheimer's trial (ACTRN12611001200976)
- You are living in the community with at least 5 hours of carer contact per week
- Your carer is willing to help you attend assessments and take medications correctly
- Women must be post-menopausal or surgically sterile
You may NOT be eligible if:
- You had significant or serious side effects during the original trial
- You have taken part in another clinical drug trial in the past 3 months
- You have a known sensitivity to selenium or sodium selenate
- You have a type of dementia other than Alzheimer's disease
- You have significant kidney, liver, or blood problems
- You take certain medications with narrow safe dose ranges (e.g. warfarin, carbamazepine)
Talk to your doctor about whether this trial might be right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Sodium selenate (VEL015) 10mg oral capsules three time daily for 24 months
Sodium selenate (VEL015) 10mg oral capsules three time daily for 24 months
Locations(3)
View Full Details on ANZCTR
For the most up-to-date information, visit the official listing.
ACTRN12613000170729