RecruitingACTRN12613000287730

Effectiveness of high intensity exercise training and vibration recovery on key health outcomes and weight control in overweight/obese people


Sponsor

University of Seville

Enrollment

50 participants

Start Date

Feb 1, 2013

Study Type

Interventional

Conditions

Summary

Exercise plays a key role in the prevention and treatment of overweight and reduction of body weight by lifestyle intervention is often modest. High intensity interval training (HIIT) characterized by repeated efforts at near-maximal to supramaximal work rates, interspersed with periods of recovery, has recently been used as an alternative to traditional endurance training to alter cardiorespiratory fitness and muscle metabolism. However, the optimal prescription with regards to intensity, work and rest duration, and number of intervals have yet to be elucidated. Alternatively, whole body vibration (WBV), which is a novel training intervention, has been proven to be a safe and effective exercise modality for improving body composition and muscle strength in deconditioned individuals. Numerous studies have indicated that WBV can decrease fat mass and increase muscle mass but also upregulate the nitric oxide dilator system and improve endothelial function which may indicate that WBV may be an effective intervention for improving health-related outcomes. To our knowledge this is the first study designed to combine both therapies; consequently, the aim of this study was to extend the previous findings examining the effects of short-term HIIT on overweight/obese people. Secondly, to determine whether vibration recovery lead to additional benefits in this population group. Methods: Fifty participants will be randomly assigned to either a HIIT training group with vibration recovery (WBVT), HIIT training group with passive recovery (HIIT) or usual-care control group (CON). Body composition (waist circumference, waist to hip ratio –WHR-, weight, height, percentage of body fat and fat-free mass), heart rate (HR), lipid-related cardiovascular risk factors (i.e. cholesterol, triglycerides, HDL, LDL, LDL/HDL and atherogenic index), Insulinemia and HOMA-index, high sensitivity-C-reactive protein and functional capacity as measured by time 6-minute walking test, hand-grip strength and lower-limb maximal strength will be assessed at baseline and after 8-weeks. Since all patients were overweight or obese, caloric intake (55% complex carbohydrates, 30% fat, and 15% protein) will be reduced to obtain a negative balance of 500 kcal/day. Requirements will be calculated by adding the estimated energy expenditure from PA to basal metabolism. WBVT participants will perform 6-10 sets x 1 min of HIIT at 90% heart rate max) followed by 6-10 x 1 min of inter-set vibration recovery at a frequency of 25 Hz and a peak to peak displacement of 4 mm. HIIT groups will perform the same HIIT followed by 4 min of passive recovery while the control group will continue their daily activities with the nutritional advice. As WBV increases leg blood flow and reduces fat mass, we hypothesize that it would provide additional therapeutic benefits to people with overweight characterized by impeded leg blood flow and abdominal obesity.


Eligibility

Sex: Both males and femalesMin Age: 20 YearssMax Age: 50 Yearss

Plain Language Summary

Simplified for easier understanding

This study is testing whether high-intensity interval training (HIIT) — short bursts of near-maximum effort exercise — combined with whole-body vibration (standing on a vibrating platform during rest periods) is more effective at improving health, fitness, and body weight in overweight or obese adults than HIIT alone or no exercise. All participants will also follow a calorie-reduced eating plan. Researchers will measure body composition, heart health, blood sugar, and cholesterol before and after 8 weeks. You may be eligible if: - You are between 20 and 50 years of age - You have a BMI of 25 kg/m² or above (overweight or obese) - You are currently sedentary (not regularly active) You may NOT be eligible if: - You have a history of advanced heart, kidney, or liver disease - You have diabetic eye, kidney, or nerve complications - You have an orthopaedic problem that prevents safe exercise - You have Type 1 or Type 2 diabetes - You are currently receiving physical therapy Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Arm 1: High Intensity Interval Training (HIIT; 6 sets and then progressively increased to 10 sets over time x 1 min of high intensity aerobic training cycling on a stationary ergometer at 90%Heart ra

Arm 1: High Intensity Interval Training (HIIT; 6 sets and then progressively increased to 10 sets over time x 1 min of high intensity aerobic training cycling on a stationary ergometer at 90%Heart rate Max) followed by 4 min of pasive recovery after each of the 1 min sets. Arm 2: the same HIIT followed by vibration recovery (1 min of inter-set recovery at a frequency of 25 Hz and a peak to peak displacement of 4 mm). In both groups caloric intake (55% complex carbohydrates, 30% fat, and 15% protein) will be reduced to obtain a negative balance of 500 kcal/day. The training sessions will be performed three times a week for 8 weeks and in all cases one-on-one supervised by an exercise physiologist


Locations(1)

Seville, Spain

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ACTRN12613000287730