The Effect of Intranasal Dexmedetomidine Premedication on the Minimum Alveolar Concentration of Sevoflurane for the Insertion of Laryngeal Mask Airway in children
The Effect of Intranasal Dexmedetomidine Premedication on Reducing the Minimum Alveolar Concentration of Sevoflurane for the Insertion of Laryngeal Mask Airway in Children
Yusheng Yao
90 participants
May 13, 2013
Interventional
Conditions
Summary
Sevoflurane is widely employed for inhalational induction of general anaesthesia in children. There is increasing evidence that dexmedetomidine is an effective and safe sedative in children. Laryngeal mask airway is an useful device for pediatric anesthesia. The aim of the current study was to determine whether Intranasal dexmedetomidine premedication can reduce MAC of sevoflurane for an LMA insertion in children
Eligibility
Inclusion Criteria1
- ASA 1 and 2 patients of either gender of the age 3- 7 years undergoing elective strabismus surgery under general anaesthesia which can be performed with LMA insertion
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Interventions
GroupD1 received 1mcg/Kg intranasal dexmedetomidine premedication 45min before general anaesthesia; GroupD2 received 2mcg/Kg intranasal dexmedetomidine premedication 45min before general anaesthesia;the intervention and the participants will be monitored throughout the duration of the procedure with follow up ending 4 hours after the procedure has been completed
Locations(1)
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ACTRN12613000462785