Open-label exploratory study of the biological activity of an Australian native food – Davidson Plum.
Open-label exploratory study of the biological activity of an Australian native food, Davidson Plum, in healthy Australian adults.
Blackmores Ltd
32 participants
Mar 25, 2013
Interventional
Conditions
Summary
Recent investigations into a range of native Australian species grown commercially for the food industry have emphasised the need for further research into the potential health benefits of these species, in particular, Davidsonia pruriens (Davidson Plum). An open label exploratory pilot study is proposed to investigate the anti-inflammatory and antioxidant effects of an extract of Davidson Plum in humans. Additionally, a range of physical and cognitive screening tests will be trialled that incorporate known markers of health status, including lung function, grip strength, mobility impairment, mood and quality of life. It is hypothesized that the oral administration of the study medication over 2 weeks will result in a statistically significant change in markers of antioxidant and anti-inflammatory status. Both smokers and non-smokers will be enrolled. The analysis will look at the total population and then at smokers and non-smokers separately.
Eligibility
Plain Language Summary
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Interventions
Aqueous extract Davidson Plum: 100mL/day to be administered orally for 2 weeks. Adherence will monitored via measurement of extract returned at completion of treatment phase.
Locations(1)
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ACTRN12613000510741