CompletedPhase 4ACTRN12613000570785
Determining the Effect of Abacavir on Platelet Activation in HIV positive men
Determining the Effect in HIV positive men of Abacavir administration on markers of Platelet Activation
Sponsor
Alfred Health
Enrollment
23 participants
Start Date
Aug 1, 2013
Study Type
Interventional
Conditions
Summary
open label single arm self-controlled trial of the affect of 15 days of abacavir on platelet function in healthy HIV positive volounteers
Eligibility
Sex: MalesMin Age: 18 Yearss
Inclusion Criteria1
- HIV positive men with well controlled HIV (undetectable viral load for > six months) on a non-abacavir containing antiretroviral regimen
Exclusion Criteria4
- Previous allergy to abacavir or HLA*B*57*01 positivity
- High Cardiovascular risk
- Platelet disorder
- Current or recent use of antiplatelets
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Interventions
Abacavir 600mg (2x 300mg oral tablets) daily for 15 days.
Adherence assessed by compliance questionaire and tablet return at day 15 visit
Abacavir 600mg (2x 300mg oral tablets) daily for 15 days. Adherence assessed by compliance questionaire and tablet return at day 15 visit
Locations(1)
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ACTRN12613000570785
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