Not Yet RecruitingPhase 2ACTRN12613000595718

ultrasound guided transversus abdominis plane block versus local wound infiltration for post-operative analgesia in children undergoing appendectomy: A Randomized Controlled Trial


Sponsor

Ahmad Ramzy

Enrollment

40 participants

Start Date

Jun 1, 2013

Study Type

Interventional

Conditions

Summary

Appendectomy is one of the most frequently performed surgical procedures in children and is associated with significant postoperative discomfort and pain.Multimodal approaches to the provision of postoperative analgesia often incorporate blockade of the abdominal wall, such as ilioinguinal blockade or wound infiltration. However, the efficacy of these approaches is unclear. This study is a prospective,randomized comparison of 2 patient groups. One group of patients will receive an ultrasound guided transversus abdominis plane (TAP) block using 0.4 ml/kg of bupivacaine 0.25% with 1:200 000 epinephrine The total dose of bupivacaine will not exceed 2 mg/kg and the total volume will not be more than 20 ml. . The second group will receive local anesthetic infiltration by the surgeon at the end of surgery for a laparoscopic appendectomy.


Eligibility

Sex: Both males and femalesMin Age: 4 YearssMax Age: 14 Yearss

Inclusion Criteria4

  • American Society of Anesthesiologists (ASA) classification score 1-2
  • Age :4 year to14years
  • Weight less than or equal to 60 kg
  • Presenting for laparoscopic appendectomy

Exclusion Criteria6

  • ASA physical status > II
  • Patients < 4 years of age
  • Weight greater than 60 kg
  • Co-morbid diseases (cardiac, pulmonary (not including asthma), neurological disease.
  • children undergoing an additional surgical procedure at an anatomical location not covered by a unilateral TAP block during the same anesthetic
  • children in whom a TAP block is contraindicated, i.e. surgical scar or distorted anatomy at the site of injection

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Interventions

This study is a prospective,randomized comparison of 2 patient groups. One group of patients will receive an ultrasound guided transversus abdominis plane (TAP) block at the end of the surgery using 0

This study is a prospective,randomized comparison of 2 patient groups. One group of patients will receive an ultrasound guided transversus abdominis plane (TAP) block at the end of the surgery using 0.4 ml/kg of bupivacaine 0.25% with 1:200 000 epinephrine The total dose of bupivacaine will not exceed 2 mg/kg and the total volume will not be more than 20 ml.


Locations(1)

Egypt

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ACTRN12613000595718