A randomised controlled study investigating neurally adjusted ventilatory assist (NAVA) application during non-invasive ventilation (NIV) in Paediatrics.
The effect of neurally adjusted ventilatory assist (NAVA) application compared to standard non invasive ventilation (NIV) on length of ventilation, length of PICU stay, oxygenation and sedation requirements in paediatrics requiring NIV.
Mater Children's Hospital
366 participants
Aug 1, 2013
Interventional
Conditions
Summary
Non-invasive ventilation (NIV) as a mode of respiratory support is growing in poopularity and a number of studies have demonstrated it's benefit in both adults and children. Difficulties associated with NIV are largely attributed to leakage around the mask which adversely affects triggering and results in a time lag between patient effort and the ventilator's response. Neurally adjusted ventilatory assist (NAVA) uses an oesophageal probe which detects diaphragmatic innervation for every breath. This results in a much more timely co-ordination of ventilatory support.
Eligibility
Inclusion Criteria1
- Requiring respiratory support using NIV
Exclusion Criteria3
- Facial and/or head injuries that prohibit application of the mask and strapping
- Inability to maintain airway
- Lack of intrinsic respiratory drive
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Interventions
Non-invasive ventilation via a mask using the neural triggering available in the mode of NAVA. Neurally Adjusted Ventilatory Assist (NAVA) is a recent highly innovative triggering design. NAVA uses an oesophageal probe which detects diaphragmatic electric activity. Diaphragmatic electric activity is the first physiological response in initiating a breath. By relying on diaphragmatic innervation the ventilator provides a timely response to patient effort that is not affected by air leaks around the face mask. The child will remain on NIV+NAVA for as long as clinically indicated.
Locations(2)
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ACTRN12613000598785