RecruitingACTRN12613000606785

Pelvic organ prolapse suspension and stapled transanal rectal resection in treatment of obstructing defecation

Pelvic organ prolapse suspension using ventral rectopexy versus stapled transanal rectal resection in treatment of obstructing defecation


Sponsor

University of Alexandria

Enrollment

80 participants

Start Date

Jun 1, 2013

Study Type

Interventional

Conditions

Summary

In the normal individual the anorectal angle is a factor in maintaining faecal continence. If intra-abdominal pressure is transmitted to the anterior rectal wall, for example during coughing or sneezing, mucosa will be forced onto the upper part of the anal canal to form a flap-valve. In patients with the descending perineum syndrome, the anorectal angle is disrupted because it lies at a lower level than normal and the patient is complaining of feeling of incomplete evacuation and straining that lead to rectorectal intussusception and/ or rectocele Correction of rectorectal intussusception and/ or rectocele can be done by stapled transanal rectal resection or abdominally by pelvic organ suspension using ventral rectopexy. Pelvic organ prolapsed suspension using ventral rectopexy and stapled transanal rectal resection can solve the anatomical problem of obstructed defecation, however no data which would have better results in multiparous females . Purpose of the study is to compare the outcome of laparoscopic ventral rectopexy versus stapled transanal rectal resection in obstructed defecation in elderly. Our hypothesis is that Laparoscopic ventral rectopexy will have better results as in these patients there is usually weakness of pelvic floor which is not supported in case of stapled transanal rectal resection Patients and Methods: 80 patients with descending perineal syndrome and obstructed defecation above 70 years of age will be treated by laparoscopic ventral mesh rectopexy or stapled transanal rectal resection by random choice ( two equal groups)


Eligibility

Sex: Both males and femalesMin Age: 70 YearssMax Age: 85 Yearss

Plain Language Summary

Simplified for easier understanding

This study is comparing two surgical procedures for elderly patients with obstructed defecation — difficulty emptying the bowel, often due to weakened pelvic floor muscles and internal rectal prolapse. One approach operates through the abdomen using a laparoscope (keyhole surgery) to lift and secure the rectum, while the other approach works through the anal canal using a stapler device to remove excess rectal tissue. Researchers want to find out which method produces better results in older patients. You may be eligible if: - You are 70 to 85 years old - You have symptoms of obstructed defecation or faecal incontinence - You have been diagnosed with perineal descent (a dropped pelvic floor) You may NOT be eligible if: - There are no specific exclusion criteria listed for this study Talk to your doctor about whether this trial might be right for you.

This is a simplified summary. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

Laparoscopic pelvic organ prolapse suspension by prolene mesh fixed to the anterior wall of rectum in one group of patients. Procedure duration approximately 120 minutes. The mesh will remain in situ

Laparoscopic pelvic organ prolapse suspension by prolene mesh fixed to the anterior wall of rectum in one group of patients. Procedure duration approximately 120 minutes. The mesh will remain in situ forever. A second new intervention group is added which receive stapled transanal rectal resection using Mini Contour stapler .


Locations(1)

Alexandria, Egypt

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ACTRN12613000606785