CompletedPhase 4ACTRN12613000775718

The effect of enoxaparin-containing irrigation fluid during cataract surgery on post-operative inflammation in patients with diabetes

The effect of enoxaparin-containing irrigation fluid during cataract surgery on post-operative inflammation in patients with diabetes; a randomized controlled clinical trial

Sponsor

Ozgur Ilhan

Enrollment

60 participants

Start Date

Aug 11, 2010

Study Type

Interventional

Conditions

post-operative inflammation after cataract surgery in patients with diabetes

Summary

The purpose of the study is to determine if intraocular infusion of low-molecular weight (enoxaparin) influences post-operative inflammation following cataract surgery in patients with diabetes

Eligibility

Sex: Both males and females

Inclusion Criteria1

The study included non-insulin-dependent diabetes mellitus (NIDDM) patients that had moderate non-proliferative diabetic retinopathy (NPDR) according to Early Treatment Diabetic Retinopathy Study (ETDRS) and had grade 2-3 nuclear cataracts based on the classification of Lens Opacity Classification System III (LOCS III)

Exclusion Criteria1

Patients who underwent laser photocoagulation in the previous three months and patients with small pupils, posterior synechia and history of uveitis were excluded from the study

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

Arm 1; Drug: Enoxaparin. It is administered during the cataract surgery. The mode of the administration is intraocular infusion. Enoxaparin 40 mg/500 ml in Balanced Salt Solution Other name: clex

Arm 1; Drug: Enoxaparin. It is administered during the cataract surgery. The mode of the administration is intraocular infusion. Enoxaparin 40 mg/500 ml in Balanced Salt Solution Other name: clexane (Aventis)

Locations(1)

Hatay, Turkey

View Full Details on ANZCTR

For the most up-to-date information, visit the official listing.

Visit

ACTRN12613000775718