Comparative study between cabergoline and intravenous calcium in the prevention of ovarian hyper stimulation in women with polycystic ovarian disease undergoing Intracytoplasmic sperm injection (ICSI ).
Comparative study between cabergoline and intravenous calcium in the prevention of ovarian hyper stimulation in women with polycystic ovarian disease undergoing ICSI .
Eman Elkattan
100 participants
Jul 15, 2013
Interventional
Conditions
Summary
we study novel approaches in the management of ovarian hyperstimulation in women suffering with Polycystic ovarian disease (PCO) and undergoing Intracytoplasmic sperm injection (ICSI).we compare the effect of intravenous calcium and oral cabergoline on the severity of ovarian hyperstimulation and outcome of ICSI as regard the pregnancy rate and miscarriage rate
Eligibility
Inclusion Criteria3
- Subfertile women with polycystic ovarian disease
- serum FSH within normal limits( 1-12IU /l)
- at least 15 follicles or more ,more than 10 mm at the time of HCG administration
Exclusion Criteria3
- patients need coasting for high risk of OHSS.
- patients need cycle cancellation.
- severe male infertility requiring testicular sperm extraction.
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Interventions
0.5 mg oral Tablets cabergoline (Dostinex) daily for 8 days from the day of HCG injection. For once in the trial To monitor the adherence to the medication we ask the patient for the drug tablet return.
Locations(1)
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ACTRN12613000904774