Impact of luteal progesterone therapy on endometrial polyps accidentally discovered during routine infertility evaluation: randomized trial.
women with detected endometrial polyps during routine infertility evaluation are randomized to receive luteal phase support by oral dydrogesterone or placebo to find out the impact on pregnancy rate and post-menstrual polyp persistence and size.
Mervat sheikhelarab Elsedeek Omran. Professor of obstetrics and gynecology, Faculty of medicine, alexandria university.
100 participants
Jun 9, 2012
Interventional
Conditions
Summary
Asymptomatic women with endometrial polyps accidentally discovered during trans-vaginal sonography done for routine infertility evaluation were either given luteal dydrogesterone for endometrial support or placebo and followed up for occurrence of pregnancy and persistence of polyp after period if no pregnancy occurred.
Eligibility
Inclusion Criteria1
- Presence of endometrial polyp in an asymptomatic regularly menstruating woman ,evaluated for infertility for one year or more, and partner normal semen.
Exclusion Criteria1
- other causes of infertility, irregular or abnormal menstrual periods
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Interventions
luteal phase support by dydrogesterone oral tablets 30 mg/day for 10 days starting 2 days after sonographically detected ovulation. cases were appointed postmenstrually to reevaluate the endometrium and make sure that they received their treatment correctly.
Locations(1)
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ACTRN12613000990729