RecruitingACTRN12613001357741

Incidence of postoperative residual curarization in the post-anaesthesia recovery unit

A study on the incidence and prevalence of postoperative residual curarization (PORC) in the post anaesthetic care unit (PACU) in female patients who underwent a general anaesthetic and received neuromuscular blocking drug (NMBD) for major gynaecological, breast , reconstructive or aesthetic surgery.


Sponsor

Dr Wendy H.L.Teoh

Enrollment

250 participants

Start Date

Dec 3, 2013

Study Type

Observational

Conditions

Summary

We aimed to characterize and define the incidence and prevalence of postoperative residual curarization (PORC) in the post anaesthetic care unit (PACU) of our tertiary referral women’s centre in 250 patients after major gynaecological, breast and aesthetic surgery. Our primary outcome variable is the incidence of PORC in awake extubated patients 10 min post-PACU arrival, where a TOF ratio <0.9 is used as criteria for defining postoperative residual weakness. Secondary outcome measures studied are the presence of side effects (nausea and vomiting), adverse respiratory events, time to PACU discharge readiness and actual length of PACU stay.


Eligibility

Sex: FemalesMin Age: 21 YearssMax Age: 80 Yearss

Plain Language Summary

Simplified for easier understanding

This study is looking at how often patients have leftover muscle weakness from anaesthetic paralysing drugs (muscle relaxants) when they wake up in the recovery room after gynaecological, breast, or cosmetic surgery. This lingering weakness, called residual neuromuscular blockade, can cause breathing difficulties. The study will also track side effects like nausea and vomiting, and how long patients stay in the recovery room. You may be eligible if: - You are a female aged between 21 and 80 years - You are having a general anaesthetic for major gynaecological, breast, reconstructive, or aesthetic surgery - You received a muscle-relaxing drug (neuromuscular blocking agent) as part of your anaesthetic - Your anaesthetic health risk is classified as ASA I, II, or III You may NOT be eligible if: - You are younger than 21 years of age - You have a neuromuscular disease that affects muscle function - You are on medications known to affect muscle-nerve communication Talk to your doctor about whether this trial might be right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

The incidence of PORC in awake extubated patients 10 min post-PACU arrival. (defined as a nerve stimulation Train Of Four ratio <0.9 for postoperative residual weakness.)

The incidence of PORC in awake extubated patients 10 min post-PACU arrival. (defined as a nerve stimulation Train Of Four ratio <0.9 for postoperative residual weakness.)


Locations(1)

Singapore, Singapore

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ACTRN12613001357741


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