The effect of perioperative intra-articular magnesium on postoperative pain after shoulder surgery

Magnesium has analgesic properties, primarily related to the antagonism of the N-methyl-o-aspartate (NMDA) receptor and the regulation of calcium influx into cells . This analgesic effect was first demonstrated in humans in 1996 when magnesium was administered intravenously in the peri-operative period . It has been reported to reduce postoperative analgesic requirements . The analgesic efficacy of intraarticular magnesium is evident after knee surgery, but its effect after shoulder surgeries has not been reported in the literature . Thus, the goal of this study is to evaluate the potential analgesic effect of magnesium when injected intraarticularly during arthroscopic shoulder surgery.