The effect of lower salt exposure at haemodialysis on cardiac micro-injury, in home and self-care haemodialysis patients.

This study is looking at whether using a lower amount of sodium (salt) in the fluid used during dialysis can reduce heart problems in people who do home or self-care haemodialysis. Researchers want to check whether any benefit is offset by low blood pressure episodes during dialysis and small amounts of heart muscle injury. You may be eligible if: - You are 18 years or older - You are on home or self-care haemodialysis for kidney failure - Your blood sodium level is 135 mmol/L or higher before dialysis - Your doctor agrees that both low and standard sodium dialysate (dialysis fluid) are suitable for you - You are willing to participate and have signed the consent form You may NOT be eligible if: - You have dialysis more than 3.5 times per week - You receive haemodiafiltration (a different type of dialysis) - Your life expectancy is less than 12 months - You are scheduled for a live-donor kidney transplant within 12 months - You have conditions that make study procedures unsafe (such as frequent low blood pressure during dialysis) - You are already enrolled in another trial testing blood pressure or dialysis changes - You have infiltrative or hereditary heart muscle disease, or moderate to severe aortic valve disease Talk to your doctor about whether this trial might be right for you.