RecruitingACTRN12614000086662

Resistance training with Partial Vascular Occlusion (VOT) in Inclusion Body Myositis (IBM). A single group interventional study: a pilot study to corroborate prior findings of VOT in the IBM population

Low intensity resistance training with blood flow to targeted muscles partially restricted: an effective strengthening regime for those with Inclusion Body Myositis?

Sponsor

Sir Charles Gairdner Hospital Physiotherapy Department

Enrollment

6 participants

Start Date

Jan 29, 2015

Study Type

Interventional

Conditions

Inclusion Body Myositis

Summary

To explore whether the relatively new form of resistance exercise which employs low resistances accompanied by restricting blood flood to targeted muscles (as know in Japan as Kaatsu training) can play a role in reducing the disability caused by inclusion body myositis.

Eligibility

Sex: Both males and females

Inclusion Criteria4

Diagnosis of Inclusion Body Myositis
A minimum of household ambulant with or without an aid
Willing to participate exclusively in the studies exercise program (ie not participate in a formal concurrent thigh strengthening program)
Full range of knee extension

Exclusion Criteria5

Non-ambulant, unable to walk 10 meters
Peripheral vascular disease and/or compromised lower limb circulation
Coexistent neurological or psychiatric disease
Severe patella-femoral pain, knee osteoarthritis
Unstable medical condition - unstable angina, uncontrolled diabetes, uncontrolled hypertension

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Interventions

1 hour, 3 times/per 18 week strength exercise program in 2 phases targeting the quadriceps muscles in people in IBM. Sessions will held in as a group and supervised by a senior physiotherapist in a t

1 hour, 3 times/per 18 week strength exercise program in 2 phases targeting the quadriceps muscles in people in IBM. Sessions will held in as a group and supervised by a senior physiotherapist in a tertiary hospital. Phase 1: establishing baseline. 5-6weeks of traditional moderate intensity strength training program (1 hour 3x/wk). Exercises: squats, leg extensions, inner range quadriceps exercises, leg press. repetitions: 8-12, 3 sets Load: approx 60% of maximum lift Phase 2: 12 weeks strength training at low intensity accompanied by partial occlusion of blood flow to quadriceps via blood pressure cuff placed around thigh. The cuff will remain inflated and around the thigh during exercises. exercises: as above repetitions: 15 load: 20-50% of maximum lift occlusion pressures: ~50% of systolic blood pressure